Anti-PANK2 antibody,Abcam,AB223091

Host

Rabbit

Reactivity

Mouse, Human

Application

IHC-P, ICC/IF, WB

Platform ID

BAB101839123

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-PANK2 antibody
Cat. No.AB223091
HostRabbit
IsotypeIgG
ReactivityMouse, Human
ApplicationIHC-P, ICC/IF, WB
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human PANK2 aa 400-500. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Isoform 1. Mitochondrial isoform that catalyzes the phosphorylation of pantothenate to generate 4'-phosphopantothenate in the first and rate-determining step of coenzyme A (CoA) synthesis (PubMed : 15659606, PubMed : 16272150, PubMed : 17242360, PubMed : 17825826). Required for angiogenic activity of umbilical vein of endothelial cells (HUVEC) (PubMed : 30221726).. Isoform 4. Cytoplasmic isoform that catalyzes the phosphorylation of pantothenate to generate 4'-phosphopantothenate in the first and rate-determining step of coenzyme A (CoA) synthesis. See full target information PANK2

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