Anti-PANK2 antibody [OTI3H9],Abcam,AB119070

Clone OTI3H9 (formerly 3H9).

Host

Mouse

Reactivity

Rat, Dog, Human, African green monkey

Application

Flow Cyt (Intra), ICC/IF, IHC-P, WB

Platform ID

BAB414345370

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-PANK2 antibody [OTI3H9]
Cat. No.AB119070
HostMouse
IsotypeIgG2a
ReactivityRat, Dog, Human, African green monkey
ApplicationFlow Cyt (Intra), ICC/IF, IHC-P, WB
ClonalityMonoclonal
Clone NumberOTI3H9
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Human PANK2.
PurityAffinity purification
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Isoform 1. Mitochondrial isoform that catalyzes the phosphorylation of pantothenate to generate 4'-phosphopantothenate in the first and rate-determining step of coenzyme A (CoA) synthesis (PubMed : 15659606, PubMed : 16272150, PubMed : 17242360, PubMed : 17825826). Required for angiogenic activity of umbilical vein of endothelial cells (HUVEC) (PubMed : 30221726).. Isoform 4. Cytoplasmic isoform that catalyzes the phosphorylation of pantothenate to generate 4'-phosphopantothenate in the first and rate-determining step of coenzyme A (CoA) synthesis. See full target information PANK2

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