Anti-PAPP A antibody [9],Abcam,AB52030

Clone number also known as 004-09.

Host

Mouse

Reactivity

Human

Application

IHC-P, IHC-Fr

Platform ID

BAB289482804

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-PAPP A antibody [9]
Cat. No.AB52030
HostMouse
IsotypeIgG2b
ReactivityHuman
ApplicationIHC-P, IHC-Fr
ClonalityMonoclonal
Clone Number9
Concentration1 mg/mL Batch dependent concentration
ImmunogenNative Full Length Protein corresponding to Human Pappalysin-1.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.097% Sodium azide Constituents: PBS, 2.9% Sodium chloride
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Metalloproteinase which specifically cleaves IGFBP-4 and IGFBP-5, resulting in release of bound IGF. Cleavage of IGFBP-4 is dramatically enhanced by the presence of IGF, whereas cleavage of IGFBP-5 is slightly inhibited by the presence of IGF. See full target information Pappalysin-1

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