Anti-PAX5 antibody [EPR3730(2)],Abcam,AB109443
What is this antibody validated in? Anti-PAX5 antibody [EPR3730(2)] (ab109443) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF), ChIP in Human, Mouse, Rat samples. What is the molecular weight of PAX5? Anti-PAX5 [EPR3730(2)] (ab109443) specifically detects a band for PAX5 (UniProt: Q02548) at a molecular weight of 42kDa. Trusted by the scientific community Anti-PAX5 [EPR3730(2)] (ab109443) was first used in a scientific publication in 2011 and has been cited over 20 times in peer-reviewed journals. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Other related products We have a range of other formats of antibody clone [EPR3730(2)] also available for your convenience: ab109443, Carrier free - ab193556 , HRP - ab202837 , Biotin - ab202956 , Alexa Fluor® 647 - ab246753 , PE - ab246754 , Alexa Fluor® 488 - ab320332 , Alexa Fluor® 555 - ab320333 , Alexa Fluor® 594 - ab320334 , APC - ab320335 , Alexa Fluor® 750 - ab320952 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Rabbit
Reactivity
Mouse, Rat, Human
Application
IHC-P, Flow Cyt (Intra), IP, ChIP, ICC/IF, WB
Platform ID
BAB853213463
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Transcription factor that plays an essential role in commitment of lymphoid progenitors to the B-lymphocyte lineage (PubMed : 10811620, PubMed : 27181361). Fulfills a dual role by repressing B-lineage inappropriate genes and simultaneously activating B-lineage-specific genes (PubMed : 10811620, PubMed : 27181361). In turn, regulates cell adhesion and migration, induces V(H)-to-D(H)J(H) recombination, facilitates pre-B-cell receptor signaling and promotes development to the mature B-cell stage (PubMed : 32612238). Repression of the cohesin-release factor WAPL causes global changes of the chromosomal architecture in pro-B cells to facilitate the generation of a diverse antibody repertoire (PubMed : 32612238).. (Microbial infection) Plays an essential role in the maintenance of Epstein-Barr virus genome copy number within the host cell by promoting EBNA1/oriP-dependent binding and transcription (PubMed : 31941781). Also participates in the inhibition of lytic EBV reactivation by modulating viral BZLF1 activity (PubMed : 23678172). See full target information PAX5
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
- Products>Primary Antibodies>Recombinant Antibodies
- Products>Trial Size Antibodies
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