Anti-PBR antibody [EPR5384],Abcam,AB109497

What is this antibody validated in? Anti-PBR antibody [EPR5384] (ab109497) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunohistochemistry (IHC-Fr), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse samples. What is the molecular weight of PBR? Anti-PBR [EPR5384] (ab109497) specifically detects a band for PBR (UniProt: P30536) at a molecular weight of 19kDa. Trusted by the scientific community Anti-PBR [EPR5384] (ab109497) was first used in a scientific publication in 2011 and has been cited over 100 times in peer-reviewed journals. Reviewed by scientists Anti-PBR [EPR5384] (ab109497) has over 10 independent reviews from customers. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Specificity confirmed The specificity of Anti-PBR antibody [EPR5384] (ab109497) has been confirmed by Western blot testing in TSPO Knockout HAP1 cell line, ab266878 . Other related products We have a range of other formats of antibody clone [EPR5384] also available for your convenience: ab109497, Alexa Fluor® 488 - ab199779 , Alexa Fluor® 647 - ab199836 , PE - ab208836 , Carrier free - ab213654 , Alexa Fluor® 555 - ab283733 , Alexa Fluor® 594 - ab303575 , Alexa Fluor® 568 - ab314401 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . Species reactivity Rat: We have preliminary internal testing data to indicate this antibody may not react with this species. Please contact us for more information.

Host

Rabbit

Reactivity

Mouse, Human

Application

Flow Cyt (Intra), ICC/IF, IHC-Fr, WB, IHC-P, IP

Platform ID

BAB666269446

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-PBR antibody [EPR5384]
Cat. No.AB109497
HostRabbit
IsotypeIgG
ReactivityMouse, Human
ApplicationFlow Cyt (Intra), ICC/IF, IHC-Fr, WB, IHC-P, IP
ClonalityMonoclonal
Clone NumberEPR5384
Concentration0.884 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme (By similarity). Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism (PubMed : 24814875), but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides (PubMed : 1847678). See full target information TSPO

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