Anti-PCGF6 antibody [EPR26301-72],Abcam,AB300059

Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Human

Application

Flow Cyt (Intra), WB, ICC/IF, IP

Platform ID

BAB229300441

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-PCGF6 antibody [EPR26301-72]
Cat. No.AB300059
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationFlow Cyt (Intra), WB, ICC/IF, IP
ClonalityMonoclonal
Clone NumberEPR26301-72
Concentration0.457 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Transcriptional repressor (PubMed : 12167161). May modulate the levels of histone H3K4Me3 by activating KDM5D histone demethylase (PubMed : 17320162). Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (PubMed : 12167161). Within the PRC1-like complex, regulates RNF2 ubiquitin ligase activity (PubMed : 26151332). See full target information PCGF6

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