Anti-PD-L1 antibody [SP142] - C-terminal,Abcam,AB228462

Anti-PD-L1 antibody [SP142] - C-terminal (ab228462) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in ICC/IF, IHC-P and mIHC. Anti-PD-L1 antibody [SP142] - C-terminal (ab228462) was first used in a scientific publication in 2016 and has been cited over 95 times in peer reviewed journals. It's performance in IHC in human and mouse samples is trusted by the scientific community. Abcam's high quality manufacturing and validation processes ensure Anti-PD-L1 antibody [SP142] - C-terminal (ab228462) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Anti-PD-L1 antibody [SP142] - C-terminal (ab228462) specifically detects PD-L1 (UniProt ID: Q9NZQ7; Molecular weight: 32kDa) and is sold in a convenient trial size to enable initial testing (20 µL) and larger sizes for subsequent scaling up experiments (100 µL, 500 µL and 1 mL). Conjugation-ready, carrier free format available for antibody clone SP142 - ab236238 . Antibody clone SP142 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor ® 647, Alexa Fluor ® 488, Alexa Fluor ® 594, Alexa Fluor ® 568, Alexa Fluor ® 555, Alexa Fluor ® 750 ( ab267563 , ab310995 , ab311750 , ab313030 , ab313231 , ab321463 ). Anti-PD-L1 antibody [SP142] - C-terminal (ab228462) is a clone from the portfolio of Spring Bioscience (Roche) SP clones which have been optimised for immunohistochemistry (IHC). PD-L1 allows tumors to escape immune detection by binding to the PD-1 receptor on T-cells, suppressing their function. Blocking this interaction with immune checkpoint inhibitors reactivates T-cells, enabling them to attack cancer cells. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .