Anti-PDE3B antibody,Abcam,AB99289
Host
Rabbit
Reactivity
Human
Application
WB, IP
Platform ID
BAB168218510
Abcam
Contact
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Product Specifications
Scientific Background
Specifications
NameAnti-PDE3B antibody
Cat. No.AB99289
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationWB, IP
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human PDE3B aa 500-550. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 - 8 Preservative: 0.09% Sodium azide Constituents: Tris citrate/phosphate
Storage+4°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological process (PubMed : 14592490, PubMed : 21393242). Regulates angiogenesis by inhibiting the cAMP-dependent guanine nucleotide exchange factor RAPGEF3 and downstream phosphatidylinositol 3-kinase gamma-mediated signaling (PubMed : 21393242). Controls cardiac contractility by reducing cAMP concentration in cardiocytes (By similarity). See full target information PDE3B
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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