Anti-PDE3B antibody,Abcam,AB42091
Host
Goat
Application
WB
Platform ID
BAB855712263
Abcam
Contact
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Product Specifications
Scientific Background
Specifications
NameAnti-PDE3B antibody
Cat. No.AB42091
HostGoat
IsotypeIgG
ApplicationWB
ClonalityPolyclonal
Concentration0.75 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human PDE3B aa 1050 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological process (PubMed : 14592490, PubMed : 21393242). Regulates angiogenesis by inhibiting the cAMP-dependent guanine nucleotide exchange factor RAPGEF3 and downstream phosphatidylinositol 3-kinase gamma-mediated signaling (PubMed : 21393242). Controls cardiac contractility by reducing cAMP concentration in cardiocytes (By similarity). See full target information PDE3B
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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