Anti-PDE3B antibody [SMCP3B],Abcam,AB95814
Host
Rat
Reactivity
Mouse
Application
WB
Platform ID
BAB418243498
Abcam
Contact
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Product Specifications
Scientific Background
Specifications
NameAnti-PDE3B antibody [SMCP3B]
Cat. No.AB95814
HostRat
IsotypeIgG2a
ReactivityMouse
ApplicationWB
ClonalityMonoclonal
Clone NumberSMCP3B
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Mouse Pde3b aa 600 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.09% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes (PubMed : 10454575). Regulates angiogenesis by inhibiting the cAMP-dependent guanine nucleotide exchange factor RAPGEF3 and downstream phosphatidylinositol 3-kinase gamma-mediated signaling (By similarity). Controls cardiac contractility by reducing cAMP concentration in cardiocytes (PubMed : 15294162). See full target information Pde3b
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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