Anti-PDE6D antibody,Abcam,AB96825

Host

Rabbit

Reactivity

Mouse, Human

Application

WB, ICC/IF, IHC-P

Platform ID

BAB168418414

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-PDE6D antibody
Cat. No.AB96825
HostRabbit
IsotypeIgG
ReactivityMouse, Human
ApplicationWB, ICC/IF, IHC-P
ClonalityPolyclonal
Concentration0.17 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human PDE6D aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 10% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Promotes the release of prenylated target proteins from cellular membranes (PubMed : 9712853). Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location (PubMed : 22002721, PubMed : 23698361). Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E (PubMed : 24166846). Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI) (By similarity). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate (By similarity). See full target information PDE6D

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