Anti-PDE6D antibody,Abcam,AB5665

Host

Rabbit

Reactivity

Mouse, Cow, Human, Pig, Sheep, Dog

Application

IHC-Fr, ICC/IF, WB, ICC

Platform ID

BAB855912167

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-PDE6D antibody
Cat. No.AB5665
HostRabbit
IsotypeIgG
ReactivityMouse, Cow, Human, Pig, Sheep, Dog
ApplicationIHC-Fr, ICC/IF, WB, ICC
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Mouse Pde6d aa 1-50. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.05% Sodium azide Constituents: PBS, 0.1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Promotes the release of prenylated target proteins from cellular membranes (PubMed : 22179043). Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location (PubMed : 22179043). Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E (By similarity). Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI) (PubMed : 22179043). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate. See full target information Pde6d

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