Anti-PDE6D antibody [HL1359] - BSA and Azide free,Abcam,AB313845

What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . Conjugation ready Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications. Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

Host

Rabbit

Reactivity

Human, Mouse, Cat, Dog, Zebrafish

Application

IHC-P, ICC/IF, WB

Platform ID

BAB480924661

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-PDE6D antibody [HL1359] - BSA and Azide free
Cat. No.AB313845
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Cat, Dog, Zebrafish
ApplicationIHC-P, ICC/IF, WB
ClonalityMonoclonal
Clone NumberHL1359
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Human PDE6D.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Constituents: PBS
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Promotes the release of prenylated target proteins from cellular membranes (PubMed : 9712853). Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location (PubMed : 22002721, PubMed : 23698361). Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E (PubMed : 24166846). Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI) (By similarity). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate (By similarity). See full target information PDE6D Additional targets Pde6d

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