Anti-PEX13 antibody,Abcam,AB96841

Target data Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor (PubMed : 28765278, PubMed : 8858165, PubMed : 9653144). The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm (By similarity). Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix (PubMed : 28765278, PubMed : 8858165, PubMed : 9653144). Involved in the import of PTS1- and PTS2-type containing proteins (PubMed : 8858165, PubMed : 9653144). See full target information PEX13