Anti-PHLDA3 antibody [4B6],Abcam,AB81464
Host
Mouse
Reactivity
Human
Application
WB
Platform ID
BAB997266813
Abcam
Contact
Tel: +44 (0)1223 696000
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Product Specifications
Scientific Background
Specifications
NameAnti-PHLDA3 antibody [4B6]
Cat. No.AB81464
HostMouse
IsotypeIgG2b
ReactivityHuman
ApplicationWB
ClonalityMonoclonal
Clone Number4B6
Concentration1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human PHLDA3 aa 1-50. The exact immunogen used to generate this antibody is proprietary information.
PurityIon exchange chromatography
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 6 - 8.5 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its direct transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May act as a tumor suppressor. See full target information PHLDA3
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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