Anti-PHOX2B antibody - N-terminal,Abcam,AB227719

Host

Rabbit

Reactivity

Human

Application

WB, IP

Platform ID

BAB873003959

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-PHOX2B antibody - N-terminal
Cat. No.AB227719
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationWB, IP
ClonalityPolyclonal
Concentration1.42 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human PHOX2B. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.025% Proclin 300 Constituents: PBS, 20% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum-response element. See full target information PHOX2B

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