Anti-PLCL1 antibody - N-terminal,Abcam,AB228627

Host

Rabbit

Reactivity

Human, Mouse

Application

IHC-P

Platform ID

BAB626377339

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-PLCL1 antibody - N-terminal
Cat. No.AB228627
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse
ApplicationIHC-P
ClonalityPolyclonal
Concentration0.92 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human PLCL1. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 10% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Involved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol. Component in the phospho-dependent endocytosis process of GABA A receptor (By similarity). Regulates the turnover of receptors and thus contributes to the maintenance of GABA-mediated synaptic inhibition. Its aberrant expression could contribute to the genesis and progression of lung carcinoma. Acts as an inhibitor of PPP1C. See full target information PLCL1

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.