Anti-PLGF antibody - N-terminal,Abcam,AB9542

According to Swissprot P49763; PLGF exists in three isoforms PLGF 1, 2 and 3. The N-terminal immunogen sequence of ab9542 is present in all isoforms so extra bands might be observed near the band of interest.

Host

Rabbit

Reactivity

Human

Application

ICC/IF, WB

Platform ID

BAB439233418

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-PLGF antibody - N-terminal
Cat. No.AB9542
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationICC/IF, WB
ClonalityPolyclonal
ImmunogenSynthetic Peptide within Human PGF. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLyophilized
ShippingBlue Ice
FormulationConstituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth. See full target information PGF

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