Anti-PMP70 antibody [CL2524],Abcam,AB211533

Target data Broad substrate specificity ATP-dependent transporter of the ATP-binding cassette (ABC) family that catalyzes the transport of long-chain fatty acids (LCFA)-CoA, dicarboxylic acids-CoA, long-branched-chain fatty acids-CoA and bile acids from the cytosol to the peroxisome lumen for beta-oxydation (PubMed : 11248239, PubMed : 24333844, PubMed : 25168382, PubMed : 29397936). Has fatty acyl-CoA thioesterase and ATPase activities (PubMed : 29397936). Probably hydrolyzes fatty acyl-CoAs into free fatty acids prior to their ATP-dependent transport into peroxisomes (By similarity). Thus, play a role in regulation of LCFAs and energy metabolism namely, in the degradation and biosynthesis of fatty acids by beta-oxidation (PubMed : 24333844, PubMed : 25944712). See full target information ABCD3