Anti-POGZ antibody,Abcam,AB171934

Host

Rabbit

Reactivity

Human

Application

WB, ICC/IF

Platform ID

BAB315370372

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-POGZ antibody
Cat. No.AB171934
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationWB, ICC/IF
ClonalityPolyclonal
ImmunogenRecombinant Fragment Protein within Human POGZ aa 1-600. The exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 6.5 - 8.5
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Plays a role in mitotic cell cycle progression and is involved in kinetochore assembly and mitotic sister chromatid cohesion. Probably through its association with CBX5 plays a role in mitotic chromosome segregation by regulating aurora kinase B/AURKB activation and AURKB and CBX5 dissociation from chromosome arms (PubMed : 20562864). Promotes the repair of DNA double-strand breaks through the homologous recombination pathway (PubMed : 26721387). See full target information POGZ

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