Anti-PPM1A antibody [7F12],Abcam,AB135249
Host
Mouse
Reactivity
Human, African green monkey
Application
ELISA, WB, Flow Cyt
Platform ID
BAB066844664
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Product Specifications
Scientific Background
Specifications
NameAnti-PPM1A antibody [7F12]
Cat. No.AB135249
HostMouse
IsotypeIgG1
ReactivityHuman, African green monkey
ApplicationELISA, WB, Flow Cyt
ClonalityMonoclonal
Clone Number7F12
ImmunogenRecombinant Fragment Protein within Human PPM1A aa 200 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.05% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Enzyme with a broad specificity. Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling. Dephosphorylates PRKAA1 and PRKAA2. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB. See full target information PPM1A
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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