Anti-PPP1R11 antibody,Abcam,AB177043

Host

Rabbit

Reactivity

Human

Application

IHC-P, WB

Platform ID

BAB004563309

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-PPP1R11 antibody
Cat. No.AB177043
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationIHC-P, WB
ClonalityPolyclonal
ImmunogenRecombinant Fragment Protein within Human PPP1R11 aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLyophilized
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Atypical E3 ubiquitin-protein ligase which ubiquitinates TLR2 at 'Lys-754' leading to its degradation by the proteasome. Plays a role in regulating inflammatory cytokine release and gram-positive bacterial clearance by functioning, in part, through the ubiquitination and degradation of TLR2 (PubMed : 27805901). Inhibitor of protein phosphatase 1 (PubMed : 9843442). See full target information PPP1R11

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.