Anti-PR3 antibody [PR3G-2],Abcam,AB240507
Host
Mouse
Reactivity
Human
Application
Flow Cyt (Intra)
Platform ID
BAB942581810
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Product Specifications
Scientific Background
Specifications
NameAnti-PR3 antibody [PR3G-2]
Cat. No.AB240507
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationFlow Cyt (Intra)
ClonalityMonoclonal
Clone NumberPR3G-2
Concentration0.1 mg/mL Batch dependent concentration
ImmunogenCell preparation containing PRTN3 protein. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationConstituents: PBS, 0.1% BSA
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) (PubMed : 2033050, PubMed : 28240246, PubMed : 3198760). By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration (PubMed : 23202369). May play a role in neutrophil transendothelial migration, probably when associated with CD177 (PubMed : 22266279). See full target information PRTN3
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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