Anti-PSD95 antibody [6G6-1C9] - Synaptic Marker,Abcam,AB2723
What is this antibody validated in? Anti-PSD95 antibody [6G6-1C9] - Synaptic Marker (ab2723) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P) in Mouse, Rat samples. What is the molecular weight of PSD95? Anti-PSD95 [6G6-1C9] - Synaptic Marker (ab2723) specifically detects a band for PSD95 (UniProt: P31016) at a molecular weight of 80kDa. Trusted by the scientific community Anti-PSD95 [6G6-1C9] - Synaptic Marker (ab2723) was first used in a scientific publication in 2003 and has been cited over 190 times in peer-reviewed journals. Reviewed by scientists Anti-PSD95 [6G6-1C9] - Synaptic Marker (ab2723) has over 10 independent reviews from customers. Other related products We have a range of other formats of antibody clone [6G6-1C9] also available for your convenience: ab2723, Carrier free - ab264091 Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact [email protected]
Host
Mouse
Reactivity
Mouse, Rat
Application
WB, IHC-P
Platform ID
BAB321567396
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Postsynaptic scaffolding protein that plays a critical role in synaptogenesis and synaptic plasticity by providing a platform for the postsynaptic clustering of crucial synaptic proteins (PubMed : 15358775, PubMed : 9853749). Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B. Also regulates AMPA-type glutamate receptor (AMPAR) immobilization at postsynaptic density keeping the channels in an activated state in the presence of glutamate and preventing synaptic depression (Probable). Under basal conditions, cooperates with FYN to stabilize palmitoyltransferase ZDHHC5 at the synaptic membrane through FYN-mediated phosphorylation of ZDHHC5 and its subsequent inhibition of association with endocytic proteins (By similarity). See full target information Dlg4
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
Please provide the required information below so that we can quickly source your products.