Anti-PTGIS/PGIS antibody,Abcam,AB23668

Host

Rabbit

Reactivity

Human, Sheep, Cow, Rat, Mouse

Application

WB, IHC-P, IHC-Fr, ICC/IF

Platform ID

BAB510510453

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-PTGIS/PGIS antibody
Cat. No.AB23668
HostRabbit
IsotypeIgG
ReactivityHuman, Sheep, Cow, Rat, Mouse
ApplicationWB, IHC-P, IHC-Fr, ICC/IF
ClonalityPolyclonal
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Mouse Ptgis aa 450-500. The exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Catalyzes the biosynthesis and metabolism of eicosanoids. Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2), a potent mediator of vasodilation and inhibitor of platelet aggregation. Additionally, displays dehydratase activity, toward hydroperoxyeicosatetraenoates (HPETEs), especially toward (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate (15(S)-HPETE). See full target information Ptgis

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