Anti-PTP1B antibody [4F8F11],Abcam,AB201974

This product was changed from ascites to supernatant. Lot no's high than GR256355-19 are from Tissue Culture Supernatant

Host

Mouse

Reactivity

Human

Application

IHC-P, WB, ICC/IF, Flow Cyt

Platform ID

BAB323166628

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-PTP1B antibody [4F8F11]
Cat. No.AB201974
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationIHC-P, WB, ICC/IF, Flow Cyt
ClonalityMonoclonal
Clone Number4F8F11
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human PTPN1 aa 1-250. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.05% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET. See full target information PTPN1

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