Anti-PTP1B antibody [EPR22474],Abcam,AB244207

What is this antibody validated in? Anti-PTP1B antibody [EPR22474] (ab244207) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse, Rat samples. What is the molecular weight of PTP1B? Anti-PTP1B [EPR22474] (ab244207) specifically detects a band for PTP1B (UniProt: P18031) at a molecular weight of 50kDa. Trusted by the scientific community Anti-PTP1B [EPR22474] (ab244207) was first used in a scientific publication in 2019 and has been cited over 10 times in peer-reviewed journals. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Specificity confirmed The specificity of Anti-PTP1B antibody [EPR22474] (ab244207) has been confirmed by Immunocytochemistry testing in PTPN1 Knockout HAP1 cell line, ab265014 . Other related products We have a range of other formats of antibody clone [EPR22474] also available for your convenience: ab244207, Carrier free - ab245984 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

WB, IP, ICC/IF, Flow Cyt (Intra), IHC-P

Platform ID

BAB135722851

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-PTP1B antibody [EPR22474]
Cat. No.AB244207
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationWB, IP, ICC/IF, Flow Cyt (Intra), IHC-P
ClonalityMonoclonal
Clone NumberEPR22474
Concentration0.53 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET. See full target information PTPN1

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