Anti-PTPN12 antibody - N-terminal,Abcam,AB154892

Host

Rabbit

Reactivity

Human

Application

WB, IHC-P, ICC/IF

Platform ID

BAB260885273

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-PTPN12 antibody - N-terminal
Cat. No.AB154892
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationWB, IHC-P, ICC/IF
ClonalityPolyclonal
Concentration0.93 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human PTPN12 aa 1-250. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 20% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades (PubMed : 18559503). Dephosphorylates cellular tyrosine kinases, such as ERBB2 and PTK2B/PYK2, and thereby regulates signaling via ERBB2 and PTK2B/PYK2 (PubMed : 17329398, PubMed : 27134172). Selectively dephosphorylates ERBB2 phosphorylated at 'Tyr-1112', 'Tyr-1196', and/or 'Tyr-1248' (PubMed : 27134172). See full target information PTPN12

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