Anti-PUMA antibody - C-terminal,Abcam,AB227130
Host
Rabbit
Reactivity
Human
Application
IP, WB, IHC-P
Platform ID
BAB261185129
Abcam
Contact
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Product Specifications
Scientific Background
Specifications
NameAnti-PUMA antibody - C-terminal
Cat. No.AB227130
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationIP, WB, IHC-P
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human BBC3. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 10% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis (PubMed : 11463391, PubMed : 23340338). Promotes partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53, releasing the bound p53/TP53 to induce apoptosis (PubMed : 23340338). Regulates ER stress-induced neuronal apoptosis (By similarity). See full target information BBC3
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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