Anti-Parvalbumin antibody,Abcam,AB11427

Anti-Parvalbumin antibody (ab11427) is a rabbit polyclonal antibody and is validated for use in ICC/IF, IHC-P in human, mouse, rat samples. Anti-Parvalbumin antibody (ab11427) has been cited over 285 times in peer reviewed journals and is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-Parvalbumin antibody (ab11427) has high sensitivity and specificity. Anti-Parvalbumin antibody (ab11427) has 30 independent reviews from customers. Anti-Parvalbumin antibody (ab11427) specifically detects Parvalbumin (UniProt ID: P20472; Molecular weight: 12kDa) and is sold in 50 µg selling sizes. Parvalbumin is a calcium-binding protein predominantly found in fast-spiking interneurons in the brain. It plays a critical role in regulating intracellular calcium levels and neurotransmission. Altered parvalbumin expression is associated with several neurological disorders, including epilepsy, schizophrenia, and autism spectrum disorders, where it affects neuronal excitability and synaptic function.

Host

Rabbit

Reactivity

Rat, Human

Application

ICC/IF, IHC-P

Platform ID

BAB040457336

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Parvalbumin antibody
Cat. No.AB11427
HostRabbit
IsotypeIgG
ReactivityRat, Human
ApplicationICC/IF, IHC-P
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenNative Full Length Protein corresponding to Rat Pvalb.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 6.5 Preservative: 0.1% Sodium azide Constituents: 2% BSA, 1.62% Sodium phosphate
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions. See full target information PVALB

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