Anti-Peripherin antibody [8G2],Abcam,AB4653

Host

Mouse

Reactivity

Mouse, Rat, Cow, Human

Application

ICC/IF, WB

Platform ID

BAB745342737

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Peripherin antibody [8G2]
Cat. No.AB4653
HostMouse
IsotypeIgG1
ReactivityMouse, Rat, Cow, Human
ApplicationICC/IF, WB
ClonalityMonoclonal
Clone Number8G2
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Rat Prph.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.032% Sodium azide Constituents: PBS, 49.98% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Class-III neuronal intermediate filament protein (PubMed : 2624740, PubMed : 3339087). My form an independent structural network without the involvement of other neurofilaments or may cooperate with the neuronal intermediate filament proteins NEFL, NEFH, NEFM and INA to form a filamentous network (By similarity). Assembly of the neuronal intermediate filaments may be regulated by RAB7A (By similarity). Plays a role in the development of unmyelinated sensory neurons (By similarity). May be involved in axon elongation and axon regeneration after injury (PubMed : 2585054, PubMed : 7530776). Inhibits neurite extension in type II spiral ganglion neurons in the cochlea (By similarity). See full target information Prph

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