Anti-Peroxiredoxin 1/PAG antibody,Abcam,AB15571

Host

Rabbit

Reactivity

Human, African green monkey

Application

WB, ICC/IF, IHC-P

Platform ID

BAB370455183

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Peroxiredoxin 1/PAG antibody
Cat. No.AB15571
HostRabbit
IsotypeIgG
ReactivityHuman, African green monkey
ApplicationWB, ICC/IF, IHC-P
ClonalityPolyclonal
ImmunogenSynthetic Peptide within Human PRDX1 aa 100-150. The exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.05% Sodium azide
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2) (PubMed : 9497357). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation (By similarity). See full target information PRDX1

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