Anti-Peroxiredoxin 3/PRDX3 antibody,Abcam,AB264354

Host

Rabbit

Reactivity

Mouse, Human

Application

IP, IHC-P, WB

Platform ID

BAB745542641

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Peroxiredoxin 3/PRDX3 antibody
Cat. No.AB264354
HostRabbit
IsotypeIgG
ReactivityMouse, Human
ApplicationIP, IHC-P, WB
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human PRDX3 aa 200 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 - 8 Preservative: 0.09% Sodium azide Constituents: Tris citrate/phosphate
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides (PubMed : 17707404, PubMed : 29438714, PubMed : 33889951, PubMed : 7733872). Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol (PubMed : 12492477). Required for the maintenance of physical strength (By similarity). See full target information PRDX3

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