Anti-Phospholipase C beta 2/PLCB2 antibody,Abcam,AB272919
Host
Rabbit
Reactivity
Human
Application
ICC/IF, WB, IHC-P
Platform ID
BAB310072916
Abcam
Contact
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Product Specifications
Scientific Background
Specifications
NameAnti-Phospholipase C beta 2/PLCB2 antibody
Cat. No.AB272919
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationICC/IF, WB, IHC-P
ClonalityPolyclonal
Concentration0.71 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human PLCB2. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.025% Proclin 300 Constituents: PBS, 20% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes (PubMed : 1644792, PubMed : 9188725). In neutrophils, participates in a phospholipase C-activating N-formyl peptide-activated GPCR (G protein-coupled receptor) signaling pathway by promoting RASGRP4 activation by DAG, to promote neutrophil functional responses (By similarity). See full target information PLCB2
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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