Anti-Phospholipase C beta 2/PLCB2 antibody - C-terminal,Abcam,AB220285

Host

Rabbit

Reactivity

Human

Application

WB, ICC/IF

Platform ID

BAB622579163

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-Phospholipase C beta 2/PLCB2 antibody - C-terminal
Cat. No.AB220285
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationWB, ICC/IF
ClonalityPolyclonal
Concentration0.2 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human PLCB2 aa 1050 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes (PubMed : 1644792, PubMed : 9188725). In neutrophils, participates in a phospholipase C-activating N-formyl peptide-activated GPCR (G protein-coupled receptor) signaling pathway by promoting RASGRP4 activation by DAG, to promote neutrophil functional responses (By similarity). See full target information PLCB2

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