Anti-Phospholipase C gamma 1/PLC-gamma-1 antibody [M156],Abcam,AB41433

Host

Mouse

Reactivity

Mouse, Human

Application

WB, Flow Cyt (Intra)

Platform ID

BAB310172868

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-Phospholipase C gamma 1/PLC-gamma-1 antibody [M156]
Cat. No.AB41433
HostMouse
IsotypeIgG1
ReactivityMouse, Human
ApplicationWB, Flow Cyt (Intra)
ClonalityMonoclonal
Clone NumberM156
ImmunogenSynthetic Peptide within Human PLCG1. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.05% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, EGFR, FGFR1, FGFR2, FGFR3 and FGFR4 (By similarity). Plays a role in actin reorganization and cell migration (PubMed : 17229814). Guanine nucleotide exchange factor that binds the GTPase DNM1 and catalyzes the dissociation of GDP, allowing a GTP molecule to bind in its place, therefore enhancing DNM1-dependent endocytosis (By similarity). See full target information PLCG1

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.