Anti-Plexin D1 antibody,Abcam,AB28762

Host

Goat

Reactivity

Human, Mouse

Application

IHC-P, ICC/IF, Flow Cyt (Intra)

Platform ID

BAB689158454

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-Plexin D1 antibody
Cat. No.AB28762
HostGoat
IsotypeIgG
ReactivityHuman, Mouse
ApplicationIHC-P, ICC/IF, Flow Cyt (Intra)
ClonalityPolyclonal
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human PLXND1 aa 1650-1700. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.3 Preservative: 0.02% Sodium azide Constituents: 0.5% BSA, 0.5% Tris
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. Plays an important role in cell-cell signaling, and in regulating the migration of a wide spectrum of cell types. Regulates the migration of thymocytes in the medulla. Regulates endothelial cell migration. Plays an important role in ensuring the specificity of synapse formation. Required for normal development of the heart and vasculature (By similarity). Mediates anti-angiogenic signaling in response to SEMA3E. See full target information PLXND1

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