Anti-Profilin 1 antibody - Carboxyterminal end,Abcam,AB50667

Host

Rabbit

Reactivity

Mouse

Application

IP

Platform ID

BAB006662301

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Profilin 1 antibody - Carboxyterminal end
Cat. No.AB50667
HostRabbit
IsotypeIgG
ReactivityMouse
ApplicationIP
ClonalityPolyclonal
Concentration1.4 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human PFN1 aa 100 to C-terminus conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.097% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR. See full target information PFN1

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.