Anti-Progesterone Receptor antibody [SP42],Abcam,AB101688

What is this antibody validated in? Anti-RAB10 antibody [MJF-R23] ( ab237703 ) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunoprecipitation (IP), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse, Rat samples. What is the molecular weight of RAB10? Anti-RAB10 [MJF-R23] ( ab237703 ) specifically detects a band for RAB10 (UniProt: P61026) at a molecular weight of 22kDa. Trusted by the scientific community Anti-RAB10 [MJF-R23] ( ab237703 ) was first used in a scientific publication in 2018 and has been cited over 20 times in peer-reviewed journals. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Specificity confirmed The specificity of Anti-RAB10 antibody [MJF-R23] ( ab237703 ) has been confirmed by Immunocytochemistry testing in RAB10 Knockout A549 cells. Other related products We have a range of other formats of antibody clone [MJF-R23] also available for your convenience: ab237703 , Carrier free - ab238655 , Alexa Fluor® 488 - ab302654 , Alexa Fluor® 647 - ab302699 , Alexa Fluor® 594 - ab302835 , Alexa Fluor® 555 - ab306567 , ab307296 , Carrier free - ab307297

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

ICC/IF, IHC-P, Flow Cyt

Platform ID

BAB944380946

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Progesterone Receptor antibody [SP42]
Cat. No.AB101688
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationICC/IF, IHC-P, Flow Cyt
ClonalityMonoclonal
Clone NumberSP42
Concentration0.242 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A/G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.6 Preservative: 0.1% Sodium azide Constituents: PBS, 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Depending on the isoform, progesterone receptor functions as a transcriptional activator or repressor.. Isoform A. Ligand-dependent transdominant repressor of steroid hormone receptor transcriptional activity including repression of its isoform B, MR and ER. Transrepressional activity may involve recruitment of corepressor NCOR2.. Isoform B. Transcriptional activator of several progesteron-dependent promoters in a variety of cell types. Involved in activation of SRC-dependent MAPK signaling on hormone stimulation.. Isoform 4. Increases mitochondrial membrane potential and cellular respiration upon stimulation by progesterone. See full target information PGR

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