Anti-Properdin/PFC antibody [10-18],Abcam,AB58984

REACH authorisation Abcam has not and does not intend to apply for the REACH Authorisation of customers' uses of products that contain European Authorisation list (Annex XIV) substances. It is the responsibility of our customers to check the necessity of application of REACH Authorisation, and any other relevant authorisations, for their intended uses.

Host

Mouse

Reactivity

Human

Application

ELISA, FuncS (Neut/Block), IHC-Fr

Platform ID

BAB944780754

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Properdin/PFC antibody [10-18]
Cat. No.AB58984
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationELISA, FuncS (Neut/Block), IHC-Fr
ClonalityMonoclonal
Clone Number10-18
Concentration1 mg/mL Batch dependent concentration
ImmunogenNative Full Length Protein corresponding to Human CFP.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 8.2 Preservative: 0.1% Sodium azide Constituents: 99% Borate buffered saline
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data A positive regulator of the alternate pathway (AP) of complement (PubMed : 20382442, PubMed : 28264884). It binds to and stabilizes the C3- and C5-convertase enzyme complexes (PubMed : 20382442, PubMed : 28264884). Inhibits CFI-CFH mediated degradation of Complement C3 beta chain (C3b) (PubMed : 31507604). See full target information CFP

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