Anti-Proteasome 19S S5A/ASF antibody [AH1.1],Abcam,AB20239

Host

Mouse

Reactivity

Human

Application

IP, Flow Cyt

Platform ID

BAB820218044

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Proteasome 19S S5A/ASF antibody [AH1.1]
Cat. No.AB20239
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationIP, Flow Cyt
ClonalityMonoclonal
Clone NumberAH1.1
Concentration1 mg/mL Batch dependent concentration
PurityAffinity purification Protein A/G
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.02% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMD4 acts as an ubiquitin receptor subunit through ubiquitin-interacting motifs and selects ubiquitin-conjugates for destruction. Displays a preferred selectivity for longer polyubiquitin chains. See full target information PSMD4

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