Anti-Proteasome 26S S2/PSMD2 antibody,Abcam,AB26078

Host

Goat

Reactivity

Mouse, Rat, Human

Application

WB, ICC/IF, Flow Cyt (Intra)

Platform ID

BAB632974171

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Proteasome 26S S2/PSMD2 antibody
Cat. No.AB26078
HostGoat
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationWB, ICC/IF, Flow Cyt (Intra)
ClonalityPolyclonal
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human PSMD2 aa 850 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.3 Preservative: 0.02% Sodium azide Constituents: 0.5% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.. Binds to the intracellular domain of tumor necrosis factor type 1 receptor. The binding domain of TRAP1 and TRAP2 resides outside the death domain of TNFR1. See full target information PSMD2

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