Anti-RAB27A + RAB27B antibody [1G7],Abcam,AB55667
What is this antibody validated in? Anti-RAB27A + RAB27B antibody [1G7] (ab55667) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse, Rat samples. What is the molecular weight of RAB27A? Anti-RAB27A + RAB27B [1G7] (ab55667) detects a band for RAB27A (UniProt: P51159) at a molecular weight of 25kDa. Trusted by the scientific community Anti-RAB27A + RAB27B [1G7] (ab55667) was first used in a scientific publication in 2007 and has been cited over 40 times in peer-reviewed journals. Reviewed by scientists Anti-RAB27A + RAB27B [1G7] (ab55667) has over 10 independent reviews from customers.
Host
Mouse
Reactivity
Human, Mouse, Rat
Application
IP, IHC-P, ICC/IF, IHC-FoFr, WB
Platform ID
BAB075040728
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (PubMed : 30771381). RAB27A regulates homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion (PubMed : 30771381). Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse (PubMed : 18812475). See full target information RAB27A Additional targets RAB27B
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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