Anti-RAD18 antibody,Abcam,AB188235

Host

Rabbit

Reactivity

Mouse, Human

Application

ICC/IF, IP, WB

Platform ID

BAB263683929

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-RAD18 antibody
Cat. No.AB188235
HostRabbit
IsotypeIgG
ReactivityMouse, Human
ApplicationICC/IF, IP, WB
ClonalityPolyclonal
ImmunogenRecombinant Fragment Protein within Human RAD18 aa 250 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.05% Sodium azide
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data E3 ubiquitin-protein ligase involved in postreplication repair of UV-damaged DNA. Postreplication repair functions in gap-filling of a daughter strand on replication of damaged DNA. Associates to the E2 ubiquitin conjugating enzyme UBE2B to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'. Has ssDNA binding activity. See full target information RAD18

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