Anti-RANK antibody [64C1385],Abcam,AB13918

Host

Mouse

Reactivity

Mouse, Human

Application

IHC-P, IP

Platform ID

BAB452227178

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-RANK antibody [64C1385]
Cat. No.AB13918
HostMouse
IsotypeIgG1
ReactivityMouse, Human
ApplicationIHC-P, IP
ClonalityMonoclonal
Clone Number64C1385
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human TNFRSF11A. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis (PubMed : 9878548). Its interaction with EEIG1 promotes osteoclastogenesis via facilitating the transcription of NFATC1 and activation of PLCG2 (By similarity). Involved in the regulation of interactions between T-cells and dendritic cells (By similarity). See full target information TNFRSF11A

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