Anti-RANK antibody [8H8B2],Abcam,AB233817
Host
Mouse
Reactivity
Human
Application
Flow Cyt, WB
Platform ID
BAB764733425
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
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Product Specifications
Scientific Background
Specifications
NameAnti-RANK antibody [8H8B2]
Cat. No.AB233817
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationFlow Cyt, WB
ClonalityMonoclonal
Clone Number8H8B2
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human TNFRSF11A aa 1-250. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.05% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis (PubMed : 9878548). Its interaction with EEIG1 promotes osteoclastogenesis via facilitating the transcription of NFATC1 and activation of PLCG2 (By similarity). Involved in the regulation of interactions between T-cells and dendritic cells (By similarity). See full target information TNFRSF11A
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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