Anti-RGS10 antibody [EPR10657(B)],Abcam,AB154172

Species reactivity Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Human

Application

WB, ICC/IF, IHC-P

Platform ID

BAB581387680

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-RGS10 antibody [EPR10657(B)]
Cat. No.AB154172
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationWB, ICC/IF, IHC-P
ClonalityMonoclonal
Clone NumberEPR10657(B)
Concentration1.055 - 1.098 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the muscarinic acetylcholine receptor CHRM2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed : 10608901, PubMed : 11443111, PubMed : 18434541, PubMed : 8774883, PubMed : 9353196). Modulates the activity of potassium channels that are activated in response to CHRM2 signaling (PubMed : 11443111). Activity on GNAZ is inhibited by palmitoylation of the G-protein (PubMed : 9353196). See full target information RGS10

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