Anti-RNF13 antibody - C-terminal,Abcam,AB151601

Host

Rabbit

Reactivity

Human

Application

IHC-P, WB, ICC/IF

Platform ID

BAB083436696

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-RNF13 antibody - C-terminal
Cat. No.AB151601
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationIHC-P, WB, ICC/IF
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human RNF13 aa 300 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: PBS, 10% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data E3 ubiquitin-protein ligase that regulates cell proliferation (PubMed : 18794910, PubMed : 23378536, PubMed : 30595371). Involved in apoptosis regulation (PubMed : 23378536, PubMed : 30595371). Mediates ER stress-induced activation of JNK signaling pathway and apoptosis by promoting ERN1 activation and splicing of XBP1 mRNA (PubMed : 23378536, PubMed : 30595371). Also involved in protein trafficking and localization (PubMed : 24387786). See full target information RNF13

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