Anti-RNase H1 antibody [HL2343],Abcam,AB317203

Host

Rabbit

Reactivity

Human, Mouse, Dog

Application

IHC-P, WB

Platform ID

BAB583286768

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-RNase H1 antibody [HL2343]
Cat. No.AB317203
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Dog
ApplicationIHC-P, WB
ClonalityMonoclonal
Clone NumberHL2343
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human RNASEH1.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Endonuclease that specifically degrades the RNA of RNA-DNA hybrids (PubMed : 10497183). Plays a role in RNA polymerase II (RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II (PubMed : 21700224). See full target information RNASEH1

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