Anti-RREB1 antibody,Abcam,AB113287

Host

Rabbit

Reactivity

Human

Application

IP

Platform ID

BAB273679129

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-RREB1 antibody
Cat. No.AB113287
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationIP
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human RREB1 aa 1350-1450. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 - 8 Preservative: 0.09% Sodium azide Constituents: 99% Tris citrate/phosphate
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Transcription factor that binds specifically to the RAS-responsive elements (RRE) of gene promoters (PubMed : 10390538, PubMed : 15067362, PubMed : 17550981, PubMed : 8816445, PubMed : 9305772). Represses the angiotensinogen gene (PubMed : 15067362). Negatively regulates the transcriptional activity of AR (PubMed : 17550981). Potentiates the transcriptional activity of NEUROD1 (PubMed : 12482979). Promotes brown adipocyte differentiation (By similarity). May be involved in Ras/Raf-mediated cell differentiation by enhancing calcitonin expression (PubMed : 8816445). See full target information RREB1

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